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Multiple Choice

What is the typical dextrose administration for a pediatric patient (not newborn) in hypoglycemia?

In pediatric hypoglycemia, the goal is to raise blood glucose quickly with a bolus of dextrose at about 0.5 g per kilogram of body weight. Using a concentrated 25% dextrose solution to deliver this dose is standard because it provides the required amount of glucose with a practical IV volume. Specifically, giving 2 mL per kilogram of a 25% dextrose solution (D25) delivers 0.5 g/kg (since 25 g per 100 mL equals 0.25 g per mL, and 2 mL/kg × 0.25 g/mL = 0.5 g/kg). This keeps the volume reasonable and aligns with common pediatric protocols. If you used a different combination, you’d either underdose or overdose. For example, 1 mL/kg of D25 would be only 0.25 g/kg, and 3 mL/kg of D25 would be 0.75 g/kg. A 5 mL/kg dose of D10 would deliver the same 0.5 g/kg but involves a larger IV volume, which is less efficient and more burdensome in a small child. Therefore, 2 mL/kg of D25 is the typical, most practical choice.

In pediatric hypoglycemia, the goal is to raise blood glucose quickly with a bolus of dextrose at about 0.5 g per kilogram of body weight. Using a concentrated 25% dextrose solution to deliver this dose is standard because it provides the required amount of glucose with a practical IV volume. Specifically, giving 2 mL per kilogram of a 25% dextrose solution (D25) delivers 0.5 g/kg (since 25 g per 100 mL equals 0.25 g per mL, and 2 mL/kg × 0.25 g/mL = 0.5 g/kg). This keeps the volume reasonable and aligns with common pediatric protocols.

If you used a different combination, you’d either underdose or overdose. For example, 1 mL/kg of D25 would be only 0.25 g/kg, and 3 mL/kg of D25 would be 0.75 g/kg. A 5 mL/kg dose of D10 would deliver the same 0.5 g/kg but involves a larger IV volume, which is less efficient and more burdensome in a small child. Therefore, 2 mL/kg of D25 is the typical, most practical choice.