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Multiple Choice

What is the epinephrine dose in PEA/Asystole as per protocol?

In cardiac arrest like PEA or asystole, epinephrine is used to increase coronary and cerebral perfusion by causing vasoconstriction. The standard adult protocol uses 1 mg given IV or IO every 3–5 minutes, using a 1:10,000 concentration. This dose reliably contributes to improved perfusion pressures during CPR without the risks associated with higher doses, and it’s repeated at defined intervals as long CPR continues. Larger doses (for example, 2 mg or 5 mg) aren’t aligned with current guidelines and don’t improve outcomes, while smaller single doses (such as 0.5 mg) aren’t considered sufficient per protocol. If IV access isn’t ready, establish IO access and administer the same 1 mg dose at 3–5 minute intervals.

In cardiac arrest like PEA or asystole, epinephrine is used to increase coronary and cerebral perfusion by causing vasoconstriction. The standard adult protocol uses 1 mg given IV or IO every 3–5 minutes, using a 1:10,000 concentration. This dose reliably contributes to improved perfusion pressures during CPR without the risks associated with higher doses, and it’s repeated at defined intervals as long CPR continues. Larger doses (for example, 2 mg or 5 mg) aren’t aligned with current guidelines and don’t improve outcomes, while smaller single doses (such as 0.5 mg) aren’t considered sufficient per protocol. If IV access isn’t ready, establish IO access and administer the same 1 mg dose at 3–5 minute intervals.